Show HN: Best biological age model using standard blood tests

1 point

8 months ago

There’s a fairly recent research paper introducing a biological age calculation model, that uses only standard blood tests and outperforms PhenoAge. So I reached out to the original researchers and did a 1-hour+ interview with one of the authors. I developed an online calculator based on it and we came up with a name for it: "Bortz Blood Age Calculator"

*About the model:*

- Trained on 306k individuals from the UK Biobank database - Validated on similar dataset - It offers an 11% relative increase in predictive value over the Levine PhenoAge - This model includes better markers (like Cystatin-C, ApoA1...) compared to other similar models. - Interesting thing is that the model selected for higher total cholesterol, ALT and creatinine as better. More about it later.

*Online calculator:*

Based on the model, I created 100% free and private online calculator: https://www.longevity-tools.com/humanitys-bortz-blood-age

*Video*

I also made a video about the calculator, which explains:

- more info about the model and how it was created - gotchas of the calcutor - some speculation about why the model selected for higher total cholesterol, ALT and creatinine

Video link: https://www.youtube.com/watch?v=2VHIfouvcYE

*Research paper link:*

https://www.nature.com/articles/s42003-023-05456-z

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I do not sell anything or promote anything paid. This is not a medical advice.

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